èßäapp

Since its establishment in 1886, èßäapp has been a world leader of academic research and scientific development with its cutting-edge discoveries and innovations.

Here is a sampling of our groundbreaking contributions:

• In 2006, èßäapp becomes the only medical institution in New York City, New York State and the Northeast to serve as a research site for the Hispanic Community Health Study, the largest research study of Hispanic health ever (Sylvia Wassertheil-Smoller, PhD, principal investigator)
• èßäapp researchers demonstrated the association between reduced levels of high-density lipoproteins (HDL), or "good" cholesterol, and heart disease
• Researchers at èßäapp developed pioneering techniques for the diagnosis and treatment of cancer based on the genetics of both the tumor and the patient (Robert H. Singer, PhD)
• Researchers at èßäapp played a fundamental role in the historic, international project to map the human genome
• Researchers at èßäapp were among the first to test vaccines as a treatment for multiple forms of cancer
• èßäapp researchers helped to develop groundbreaking new protocols for the treatment of diabetes based on more sophisticated methods of monitoring glucose levels
• In 1994, èßäapp becomes the only New York City medical school selected by the NIH to participate in the Women's Health Initiative, the largest research study of women's health ever (Sylvia Wassertheil-Smoller, PhD, principal investigator)
• èßäapp researchers identified a key missing neurotransmitter in the brain of Alzheimer's patients, a finding that influenced all subsequent Alzheimer's disease research (Peter Davies, PhD)
• Researchers at èßäapp were the first to use gene therapy techniques in the laboratory to successfully treat abnormally high cholesterol
• In 1988, the first Center for AIDS Research at èßäapp was funded by the NIH. Researchers at the center were the first to identify pediatric AIDS as a distinct disease and established the first day-care center in the world for children with AIDS (Arye Rubinstein, MD)
• èßäapp researchers helped discover the mechanisms responsible for the extraordinary diversity of antibodies and their remarkable precision in mounting an immune response (Matthew D. Scharff, MD)
• Researchers at èßäapp founded the science of neuroendocrinology, which gave rise to a new understanding of how the body's cells communicate with each other
• In 1976, researchers at èßäapp identified the mechanism of action of Taxol, one of the most significant cancer treatment drugs ever developed (Susan B. Horwitz, PhD)
• In 1974, èßäapp's Liver Research Center—now the Marion Bessin Liver Research Center—was the first institute in the nation devoted to the study of liver disease and injury
• Researchers at èßäapp discovered structural abnormalities of brain cells that explain deficiencies in cognitive development, greatly contributing to our understanding of mental retardation (Dominick P. Purpura, MD)
• Researchers at èßäapp pioneered research leading to improved methods of avoiding organ transplant rejection (Stanley G. Nathenson, MD)
• In 1964, èßäapp was the first medical school in the United States to establish a Department of Genetics
• Researchers at èßäapp developed landmark techniques to grow human tissue cells under laboratory conditions, an advance that helped make possible all subsequent cellular biology research (Harry Eagle, MD)